≡ Risteys
R10

Documentation Changelog GitHub Contact & Feedback

Vascular dementia

DOID EFO MESH SNOMED Endpoint Browser PheWeb

F5_VASCDEM

vascular dementia: A degenerative vascular disorder affecting the brain. It is caused by the blockage of the blood supply to the brain. It is manifested with decline of memory and cognitive functions.

Endpoint definition

↥
FinnGen phenotype data

429209 individuals

diagram downward connector

Apply sex-specific rule None

429209

diagram downward connector

Check conditions None

429209

diagram downward connector
diagram bullet

Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 F01
Hospital discharge: ICD-9 4378
Cause of death: ICD-10 F01
Cause of death: ICD-9 4378

2 out of 7 registries used, show all original rules.

2802

diagram downward connector

Check minimum number of events None

2802

diagram downward connector

Include endpoints None

2802

diagram downward connector
diagram bullet diagram downward connector

Remove individuals based on genotype QC

2717

diagram downward connector
F5_VASCDEM

Control definitions

Control exclude F5_DEMENTIA

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 F00-F03
Name in latin Dementia vascularis

Summary Statistics

↥

Key figures

All Female Male
Number of individuals 2717 907 1810
Unadjusted prevalence (%) 0.66 0.39 1.00
Mean age at first event (years) 79.36 81.18 78.45

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.25 13.05 [11.65, 14.62] <1e-100 1778
15 years 0.02 2.47 [2.18, 2.80] 3.4e-46 304
5 years 0.01 7.57 [6.69, 8.56] <1e-100 669
1 year 0.01 26.93 [23.50, 30.85] <1e-100 796

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

↥

Index endpoint: F5_VASCDEM – Vascular dementia
GWS hits: 3

Survival analyses between endpoints

↥

Plot

before Vascular dementia
after Vascular dementia

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Vascular dementia

↥

Endpoint not on priority list, no data to show.