Psoriasis (vulgaris), strict definition


psoriasis: An autoimmune condition characterized by red, well-delineated plaques with silvery scales that are usually on the extensor surfaces and scalp. They can occasionally present with these manifestations: pustules; erythema and scaling in intertriginous areas, and erythroderma, that are often distributed on extensor surfaces and scalp.

Endpoint definition

FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None


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Check conditions



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Check pre-conditions, main-only, mode, registry filters

KELA reimbursements: KELA codes 319|377|134

1 out of 7 registries used, show all original rules.


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Check minimum number of events None


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Include endpoints None


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Remove individuals based on genotype QC


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Control definitions

Control exclude L12_PAPULOSQUAMOUS
Control conditions not L12_PSORI_VULG

Extra metadata

First used in FinnGen datafreeze DF3

Summary Statistics

Key figures

All Female Male
Number of individuals 901 348 553
Unadjusted prevalence (%) 0.22 0.15 0.30
Mean age at first event (years) 50.84 51.71 50.28


Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.05 2.73 [1.59, 4.68] 2.7e-4 66
15 years 0.01 1.44 [0.83, 2.50] 1.9e-1 26
5 years 0.00 2.38 [1.26, 4.52] 7.7e-3 12
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence


Index endpoint: PSORI_STRICT – Psoriasis (vulgaris), strict definition
GWS hits: 6

Survival analyses between endpoints


before Psoriasis (vulgaris), strict definition
after Psoriasis (vulgaris), strict definition

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Drugs most likely to be purchased after Psoriasis (vulgaris), strict definition

Endpoint not on priority list, no data to show.