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Primary gonarthrosis, bilateral

MESH Endpoint Browser PheWeb

PRIM_KNEEARTHROSIS

No definition available.

Endpoint definition

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FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 M17.0
Cause of death: ICD-10 M17.0

2 out of 7 registries used, show all original rules.

19101

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Check minimum number of events None

19101

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Include endpoints None

19101

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Remove individuals based on genotype QC

18562

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PRIM_KNEEARTHROSIS

Control definitions

Control exclude KNEE_ARTHROSIS

Extra metadata

First used in FinnGen datafreeze DF2
Parent code in ICD-10 M17
Name in latin Gonarthrosis primaria bilateralis

Summary Statistics

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Key figures

All Female Male
Number of individuals 18562 11381 7181
Unadjusted prevalence (%) 4.51 4.94 3.95
Mean age at first event (years) 64.11 63.74 64.70

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.04 1.87 [1.60, 2.20] 1.9e-14 2044
15 years 0.01 1.31 [1.14, 1.52] 2.3e-4 1126
5 years 0.00 1.64 [1.42, 1.89] 5.3e-12 464
1 year 0.00 1.93 [1.54, 2.43] 1.6e-8 100

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: PRIM_KNEEARTHROSIS – Primary gonarthrosis, bilateral
GWS hits: 36

Survival analyses between endpoints

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Plot

before Primary gonarthrosis, bilateral
after Primary gonarthrosis, bilateral

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Primary gonarthrosis, bilateral

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Endpoint not on priority list, no data to show.