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Other/unspecified synovitis and tenosynovitis

DOID EFO MESH SNOMED Endpoint Browser PheWeb

M13_TENDOSYNOVITISNAS

Tenosynovitis: Inflammation of the synovial lining of a tendon sheath. Causes include trauma, tendon stress, bacterial disease (gonorrhea, tuberculosis), rheumatic disease, and gout. Common sites are the hand, wrist, shoulder capsule, hip capsule, hamstring muscles, and Achilles tendon. The tendon sheaths become inflamed and painful, and accumulate fluid. Joint mobility is usually reduced.

Endpoint definition

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FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 M65.8, M65.9
Hospital discharge: ICD-9 7270
Hospital discharge: ICD-8 7310[0-3]
Hospital discharge: excluded ICD-9 7270A
Cause of death: ICD-10 M65.8, M65.9
Cause of death: ICD-9 7270
Cause of death: ICD-8 7310[0-3]
Cause of death: excluded ICD-9 7270A

2 out of 7 registries used, show all original rules.

4156

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Check minimum number of events None

4156

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Include endpoints None

4156

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Remove individuals based on genotype QC

4028

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M13_TENDOSYNOVITISNAS

Control definitions

Control exclude M13_SOFTTISSUE

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF4

Summary Statistics

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Key figures

All Female Male
Number of individuals 4028 2541 1487
Unadjusted prevalence (%) 0.98 1.10 0.82
Mean age at first event (years) 43.06 43.13 42.96

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.07 [0.70, 1.63] 7.6e-1 325
15 years 0.01 0.77 [0.53, 1.12] 1.7e-1 127
5 years 0.00 0.96 [0.62, 1.47] 8.4e-1 42
1 year 0.00 2.11 [1.18, 3.75] 1.1e-2 16

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: M13_TENDOSYNOVITISNAS – Other/unspecified synovitis and tenosynovitis
GWS hits: 1

Survival analyses between endpoints

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Plot

before Other/unspecified synovitis and tenosynovitis
after Other/unspecified synovitis and tenosynovitis

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Drugs most likely to be purchased after Other/unspecified synovitis and tenosynovitis

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Endpoint not on priority list, no data to show.