Disorders of synovium and tendon

M13_SYNOTEND

Tendinopathy: Disorders that are causes by overuse of tendons.

Endpoint definition

FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 M65-M68
Cause of death: ICD-10 M65-M68

2 out of 7 registries used, show all original rules.

20197

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Check minimum number of events None

20197

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Remove individuals based on genotype QC

22636

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M13_SYNOTEND

Control definitions

Control exclude M13_SOFTTISSUE

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 22636 15034 7602
Unadjusted prevalence (%) 5.49 6.53 4.18
Mean age at first event (years) 47.93 47.01 49.74

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.06 [0.87, 1.28] 5.7e-1 1232
15 years 0.01 0.90 [0.76, 1.06] 2.2e-1 569
5 years 0.00 1.17 [0.97, 1.41] 1.1e-1 198
1 year 0.00 1.81 [1.35, 2.43] 7.7e-5 56

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: M13_SYNOTEND – Disorders of synovium and tendon
GWS hits: 1

Survival analyses between endpoints

Plot

before Disorders of synovium and tendon
after Disorders of synovium and tendon

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Disorders of synovium and tendon

Endpoint not on priority list, no data to show.