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Scoliosis

DOID EFO MESH SNOMED Endpoint Browser PheWeb

M13_SCOLIOSIS

scoliosis: A congenital or acquired spinal deformity characterized by lateral curvature of the spine.

Endpoint definition

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FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 M41
Hospital discharge: ICD-9 7373
Cause of death: ICD-10 M41
Cause of death: ICD-9 7373

2 out of 7 registries used, show all original rules.

2932

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Check minimum number of events None

2932

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Include endpoints None

2932

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Remove individuals based on genotype QC

2817

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M13_SCOLIOSIS

Control definitions

Control exclude M13_DORSOPATHY

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 M40-M43
Name in latin Scoliosis

Summary Statistics

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Key figures

All Female Male
Number of individuals 2817 2203 614
Unadjusted prevalence (%) 0.68 0.96 0.34
Mean age at first event (years) 41.77 41.38 43.20

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.07 3.67 [2.24, 6.02] 2.5e-7 114
15 years 0.01 1.66 [0.97, 2.84] 6.7e-2 46
5 years 0.00 3.25 [1.91, 5.55] 1.5e-5 40
1 year 0.00 5.36 [2.74, 10.52] 1.0e-6 13

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: M13_SCOLIOSIS – Scoliosis
GWS hits: 1

Survival analyses between endpoints

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Plot

before Scoliosis
after Scoliosis

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Scoliosis

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Endpoint not on priority list, no data to show.