Kyphosis

M13_KYPHOSIS

phimosis: A condition in which there is constriction in the tip of the foreskin resulting in inability to fully retract the foreskin over the glans penis. Causes include balanoposthitis, balanitis xerotica obliterans, and untreated diabetes.

Endpoint definition

FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 M40.0, M40.1, M40.2
Hospital discharge: ICD-9 737[0-1]
Cause of death: ICD-10 M40.0, M40.1, M40.2
Cause of death: ICD-9 737[0-1]

2 out of 7 registries used, show all original rules.

359

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Check minimum number of events None

359

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Include endpoints None

359

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Remove individuals based on genotype QC

347

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M13_KYPHOSIS

Control definitions

Control exclude M13_DORSOPATHY

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 347 206 141
Unadjusted prevalence (%) 0.08 0.09 0.08
Mean age at first event (years) 57.59 59.24 55.18

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: M13_KYPHOSIS – Kyphosis
GWS hits: 1

Survival analyses between endpoints

Plot

before Kyphosis
after Kyphosis

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Kyphosis

Endpoint not on priority list, no data to show.