Fibroblastic disorders

DOID EFO MESH SNOMED Endpoint Browser PheWeb

M13_FIBROBLASTIC

fibroma: A non-metastasizing neoplasm arising from the fibrous tissue. It is characterized by the presence of spindle-shaped fibroblasts.

Endpoint definition

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FinnGen phenotype data

429209 individuals

Apply sex-specific rule None

429209

Check conditions None

429209

Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 M72

Cause of death: ICD-10 M72

2 out of 7 registries used, show all original rules.

7288

Check minimum number of events None

7288

Include endpoints

M13_DUPUTRYEN

M13_KNUCKLEPADS

M13_PLANTARFASC

M13_PSEUDOSARCFIBROMATOSIS

M13_NECROFASC

M13_FIBROBLASTNAS

8975

Remove individuals based on genotype QC

8686

M13_FIBROBLASTIC

Control definitions

Control exclude M13_SOFTTISSUE

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF2

Parent code in ICD-10 M70-M79

Name in latin Morbositates fibroblasticae

NAME	M13_FIBROBLASTIC
CONTROL_EXCLUDE	M13_SOFTTISSUE
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE	M13_DUPUTRYEN\|M13_KNUCKLEPADS\|M13_PLANTARFASC\|M13_PSEUDOSARCFIBROMATOSIS\|M13_NECROFASC\|M13_FIBROBLASTNAS
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	M72
HD_ICD_9
HD_ICD_8
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	M72
COD_ICD_9
COD_ICD_8
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

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Similar endpoints

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List of similar endpoints to Fibroblastic disorders based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	8686	3709	4977
Unadjusted prevalence (%)	2.11	1.61	2.74
Mean age at first event (years)	54.12	50.44	56.86

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.03	1.37 [1.05, 1.78]	2.1e-2	1358
15 years	0.01	1.07 [0.87, 1.31]	5.2e-1	655
5 years	0.00	1.26 [1.05, 1.52]	1.4e-2	228
1 year	0.00	1.84 [1.38, 2.46]	3.9e-5	62

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: M13_FIBROBLASTIC – Fibroblastic disorders
GWS hits: 33

Survival analyses between endpoints

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Plot

before Fibroblastic disorders
after Fibroblastic disorders

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Table

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Drugs most likely to be purchased after Fibroblastic disorders

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Endpoint not on priority list, no data to show.

≡ Risteys

R10

R9

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R5

R4

R3