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Palmar fascial fibromatosis [Dupuytren]

DOID EFO MESH SNOMED Endpoint Browser PheWeb

M13_DUPUTRYEN

Plantar Fibromatosis: A superficial fibromatosis arising from soft tissue of the plantar regions. It is characterized by the presence of spindle-shaped fibroblasts, hypercellularity, and an infiltrative growth pattern.

Endpoint definition

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FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 M72.0
Hospital discharge: ICD-9 7286
Hospital discharge: ICD-8 7339
Cause of death: ICD-10 M72.0
Cause of death: ICD-9 7286
Cause of death: ICD-8 7339

2 out of 7 registries used, show all original rules.

5709

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Check minimum number of events None

5709

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Include endpoints None

5709

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Remove individuals based on genotype QC

5542

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M13_DUPUTRYEN

Control definitions

Control exclude M13_SOFTTISSUE

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 M72
Name in latin Fibromatosis aponeurosis palmaris

Summary Statistics

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Key figures

All Female Male
Number of individuals 5542 1393 4149
Unadjusted prevalence (%) 1.35 0.61 2.28
Mean age at first event (years) 55.95 51.12 57.57

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 1.29 [1.05, 1.58] 1.6e-2 1180
15 years 0.01 1.03 [0.88, 1.21] 7.2e-1 587
5 years 0.00 1.19 [1.00, 1.43] 5.2e-2 198
1 year 0.00 1.34 [0.96, 1.87] 8.6e-2 40

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: M13_DUPUTRYEN – Palmar fascial fibromatosis [Dupuytren]
GWS hits: 46

Survival analyses between endpoints

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Plot

before Palmar fascial fibromatosis [Dupuytren]
after Palmar fascial fibromatosis [Dupuytren]

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Drugs most likely to be purchased after Palmar fascial fibromatosis [Dupuytren]

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Endpoint not on priority list, no data to show.