Gonarthrosis, primary, with knee surgery

M13_ARTHROSIS_KNEE_PRIM_KNEESURG

No definition available.

Endpoint definition

FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions

M13_ARTHROSIS_KNEE_PRIM_ICD10

44989

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Check pre-conditions, main-only, mode, registry filters

Operations: NOMESCO codes ^NGB|^NGC

1 out of 7 registries used, show all original rules.

21583

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Check minimum number of events None

21583

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Include endpoints None

21583

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Remove individuals based on genotype QC

21059

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M13_ARTHROSIS_KNEE_PRIM_KNEESURG

Control definitions

Control conditions not M13_ARTHROSIS_KNEE_PRIM_ICD10

Extra metadata

Level in the ICD hierarchy C
First used in FinnGen datafreeze DF3

Summary Statistics

Key figures

All Female Male
Number of individuals 21059 12950 8109
Unadjusted prevalence (%) 5.11 5.62 4.46
Mean age at first event (years) 66.65 66.32 67.17

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 1.58 [1.27, 1.98] 5.3e-5 2132
15 years 0.01 1.24 [1.06, 1.46] 6.9e-3 1319
5 years 0.00 1.28 [1.11, 1.48] 9.7e-4 446
1 year 0.00 1.12 [0.86, 1.46] 4.0e-1 70

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: M13_ARTHROSIS_KNEE_PRIM_KNEESURG – Gonarthrosis, primary, with knee surgery
GWS hits: 44

Survival analyses between endpoints

Plot

before Gonarthrosis, primary, with knee surgery
after Gonarthrosis, primary, with knee surgery

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Gonarthrosis, primary, with knee surgery

Endpoint not on priority list, no data to show.