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Substance abuse (more control exclusions)

Endpoint Browser PheWeb

KRA_PSY_SUBSTANCE_EXMORE

No definition available.

Endpoint definition

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FinnGen phenotype data

individuals

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Apply sex-specific rule None

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Check conditions None

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 F10-F19
Hospital discharge: ICD-9 29[1-2]|30[3-5]
Hospital discharge: ICD-8 291|30[3-4]
Hospital discharge: excluded ICD-10 F10.0
Hospital discharge: excluded ICD-9 3050A
Cause of death: ICD-10 F10-F19
Cause of death: ICD-9 29[1-2]|30[3-5]
Cause of death: ICD-8 291|30[3-4]

2 out of 7 registries used, show all original rules.

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Check minimum number of events None

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Include endpoints

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Remove individuals based on genotype QC

25458

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KRA_PSY_SUBSTANCE_EXMORE

Control definitions

Control exclude KRA_PSY_ANYMENTAL

Extra metadata

First used in FinnGen datafreeze DF2

No upset plot: script not run.

No upset table: script not run.

Summary Statistics

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Key figures

All Female Male
Number of individuals 25458 9086 16372
Unadjusted prevalence (%) 6.18 3.95 9.01
Mean age at first event (years) 45.24 41.37 47.39

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.09 5.13 [4.37, 6.02] 1.9e-89 5263
15 years 0.02 3.16 [2.78, 3.58] 4.4e-70 1971
5 years 0.01 5.33 [4.80, 5.92] <1e-100 1162
1 year 0.00 25.16 [22.43, 28.24] <1e-100 1119

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: KRA_PSY_SUBSTANCE_EXMORE – Substance abuse (more control exclusions)
GWS hits: 18

Survival analyses between endpoints

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Plot

before Substance abuse (more control exclusions)
after Substance abuse (more control exclusions)

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Substance abuse (more control exclusions)

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Endpoint not on priority list, no data to show.