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Mental retardation

KRA_PSY_MENTALRET

mental retardation: ['Subnormal intellectual functioning which originates during the developmental period. This has multiple potential etiologies, including genetic defects and perinatal insults. Intelligence quotient (IQ) scores are commonly used to determine whether an individual is mentally retarded. IQ scores between 70 and 79 are in the borderline mentally retarded range. Scores below 67 are in the retarded range. (Joynt, Clinical Neurology, 1992, Ch55, p28)']

Endpoint definition

FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 F70-F79
Hospital discharge: ICD-9 31[7-9]
Hospital discharge: ICD-8 31[1-5]
Cause of death: ICD-10 F70-F79
Cause of death: ICD-9 31[7-9]
Cause of death: ICD-8 31[1-5]

2 out of 7 registries used, show all original rules.

1346

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Check minimum number of events None

1346

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Include endpoints None

1346

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Remove individuals based on genotype QC

1254

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KRA_PSY_MENTALRET

Control definitions

Controls for this endpoint are individuals that are not cases.

Extra metadata

First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 1254 617 637
Unadjusted prevalence (%) 0.30 0.27 0.35
Mean age at first event (years) 26.17 26.57 25.79

Mortality

Not a core endpoint, no data to show.

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Not a core endpoint, no data to show.

Correlations

Index endpoint: KRA_PSY_MENTALRET – Mental retardation
GWS hits:

Survival analyses between endpoints

Not a core endpoint, no data to show.

Drugs most likely to be purchased after Mental retardation

Endpoint not on priority list, no data to show.