Moderate mental retardation

F5_MODRET

mental retardation: ['Subnormal intellectual functioning which originates during the developmental period. This has multiple potential etiologies, including genetic defects and perinatal insults. Intelligence quotient (IQ) scores are commonly used to determine whether an individual is mentally retarded. IQ scores between 70 and 79 are in the borderline mentally retarded range. Scores below 67 are in the retarded range. (Joynt, Clinical Neurology, 1992, Ch55, p28)']

Endpoint definition

FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 F71
Hospital discharge: ICD-9 3180
Hospital discharge: ICD-8 312
Cause of death: ICD-10 F71
Cause of death: ICD-9 3180
Cause of death: ICD-8 312

2 out of 7 registries used, show all original rules.

202

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Check minimum number of events None

202

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Include endpoints None

202

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Remove individuals based on genotype QC

190

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F5_MODRET

Control definitions

Control exclude F5_MENTRET

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 F70-F79
Name in latin Retardatio mentalis moderata

Summary Statistics

Key figures

All Female Male
Number of individuals 190 93 97
Unadjusted prevalence (%) 0.05 0.04 0.05
Mean age at first event (years) 25.94 24.61 27.23

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: F5_MODRET – Moderate mental retardation
GWS hits: 1

Survival analyses between endpoints

Plot

before Moderate mental retardation
after Moderate mental retardation

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Drugs most likely to be purchased after Moderate mental retardation

Endpoint not on priority list, no data to show.