IBD (strict) with PSC

K11_IBD_STRICT_PSC

inflammatory bowel disease: A spectrum of small and large bowel inflammatory diseases of unknown etiology. It includes Crohn's disease, ulcerative colitis, and colitis of indeterminate type.

Endpoint definition

FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions

K11_CHOLANGI_STRICT
and K11_IBD_STRICT

309

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Check pre-conditions, main-only, mode, registry filters None

0 out of 7 registries used, show all original rules.

0

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Check minimum number of events None

0

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Include endpoints

309

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Remove individuals based on genotype QC

302

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K11_IBD_STRICT_PSC

Control definitions

Control exclude K11_IBD, K11_CHOLANGI
Control conditions not K11_CHOLANGI_STRICT
and not K11_IBD_STRICT

Extra metadata

First used in FinnGen datafreeze DF3

Summary Statistics

Key figures

All Female Male
Number of individuals 302 144 158
Unadjusted prevalence (%) 0.07 0.06 0.09
Mean age at first event (years) 29.50 29.75 29.27

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: K11_IBD_STRICT_PSC – IBD (strict) with PSC
GWS hits: 1

Survival analyses between endpoints

Plot

before IBD (strict) with PSC
after IBD (strict) with PSC

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Drugs most likely to be purchased after IBD (strict) with PSC

Endpoint not on priority list, no data to show.