This is a non-core endpoint: only basic statistics are computed.
See these related core endpoints for full statistics:
Crohn disease
DOID EFO MESH SNOMED Endpoint Browser
K11_CROHN
Crohn's disease: A gastrointestinal disorder characterized by chronic inflammation involving all layers of the intestinal wall, noncaseating granulomas affecting the intestinal wall and regional lymph nodes, and transmural fibrosis. Crohn disease most commonly involves the terminal ileum; the colon is the second most common site of involvement.
Endpoint definition
↥
FinnGen phenotype data
429209 individuals
Apply sex-specific rule None
429209
Check conditions None
429209
Check pre-conditions, main-only, mode, registry filters
Hospital Discharge: ICD-10
K50
Hospital discharge: ICD-9
555
Hospital discharge: ICD-8
5630
Cause of death: ICD-10
K50
Cause of death: ICD-9
555
Cause of death: ICD-8
5630
2 out of 7 registries used, show all original rules.
4760
Check minimum number of events None
4760
Include endpoints None
4760
Remove individuals based on genotype QC
4601
K11_CROHN
Control definitions
Control exclude
K11_ENERCOLNONINF
Extra metadata
Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
K50-K52
Name in latin
Morbus Crohn
Show upset plot detailing case counts by codes
Or the full data table
Similar endpoints
↥List of similar endpoints to
Crohn disease
based on the number of shared cases.
Broader endpoints:
- Inflammatory bowel disease
- Noninfective enteritis and colitis
- Autoimmune diseases related-to ILD
- Autoimmune diseases
- Used for control exclusion in common control thyroid runs
Narrower endpoints:
Summary Statistics
↥Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 4601 | 2548 | 2053 |
| Unadjusted prevalence (%) | 1.12 | 1.11 | 1.13 |
| Mean age at first event (years) | 42.53 | 40.79 | 44.68 |
Mortality
Not a core endpoint, no data to show.
Age distribution of first events
Year distribution of first events
Cumulative Incidence
Not a core endpoint, no data to show.
Correlations
↥
Index endpoint: K11_CROHN – Crohn disease
GWS hits:
Survival analyses between endpoints
↥Not a core endpoint, no data to show.
Drugs most likely to be purchased after Crohn disease
↥Endpoint not on priority list, no data to show.