Crohn's disease of small intestine

CHRONSMALL

No definition available.

Endpoint definition

FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 K50.0
Cause of death: ICD-10 K50.0

2 out of 7 registries used, show all original rules.

2278

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Check minimum number of events None

2278

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Include endpoints None

2278

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Remove individuals based on genotype QC

2205

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CHRONSMALL

Control definitions

Control exclude K11_ENERCOLNONINF

Extra metadata

First used in FinnGen datafreeze DF2
Parent code in ICD-10 K50
Name in latin Morbus Crohn intestini tenuis

Summary Statistics

Key figures

All Female Male
Number of individuals 2205 1260 945
Unadjusted prevalence (%) 0.54 0.55 0.52
Mean age at first event (years) 44.36 42.34 47.04

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.04 1.68 [0.92, 3.10] 9.3e-2 110
15 years 0.01 1.16 [0.70, 1.93] 5.7e-1 42
5 years 0.00 2.75 [1.69, 4.47] 4.9e-5 28
1 year 0.00 10.47 [6.15, 17.84] 5.7e-18 20

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: CHRONSMALL – Crohn's disease of small intestine
GWS hits: 8

Survival analyses between endpoints

Plot

before Crohn's disease of small intestine
after Crohn's disease of small intestine

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Drugs most likely to be purchased after Crohn's disease of small intestine

Endpoint not on priority list, no data to show.