Aortic aneurysm

I9_AORTANEUR

aortic aneurysm: A ruptured aneurysm located in the wall of the proximal portion of the descending aorta proceeding from the arch of the aorta.

Endpoint definition

FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 I71.1, I71.2, I71.3, I71.4, I71.5, I71.6, I71.8, I71.9
Hospital discharge: ICD-9 441[1-9]|0930A
Hospital discharge: ICD-8 0930|441
Cause of death: ICD-10 I71.1, I71.2, I71.3, I71.4, I71.5, I71.6, I71.8, I71.9
Cause of death: ICD-9 441[1-9]|0930A
Cause of death: ICD-8 0930|441

2 out of 7 registries used, show all original rules.

8252

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Check minimum number of events None

8252

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Include endpoints

8361

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Remove individuals based on genotype QC

8124

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I9_AORTANEUR

Control definitions

Control exclude I9_DOAAC

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 8124 1234 6890
Unadjusted prevalence (%) 1.97 0.54 3.79
Mean age at first event (years) 68.25 66.46 68.57

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.09 4.31 [3.31, 5.61] 2.8e-27 2626
15 years 0.01 1.99 [1.57, 2.51] 1.2e-8 954
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: I9_AORTANEUR – Aortic aneurysm
GWS hits: 24

Survival analyses between endpoints

Plot

before Aortic aneurysm
after Aortic aneurysm

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Aortic aneurysm

Endpoint not on priority list, no data to show.