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Diseases of middle ear and mastoid

DOID EFO MESH SNOMED Endpoint Browser PheWeb

H8_MIDDLEMASTOID

suppurative otitis media: Inflammation of the middle ear with purulent discharge.

Endpoint definition

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FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 H65-H75
Cause of death: ICD-10 H65-H75

2 out of 7 registries used, show all original rules.

18163

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Check minimum number of events None

18163

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Include endpoints

28717

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Remove individuals based on genotype QC

27527

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H8_MIDDLEMASTOID

Control definitions

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF2

Summary Statistics

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Key figures

All Female Male
Number of individuals 27527 15894 11633
Unadjusted prevalence (%) 6.68 6.90 6.40
Mean age at first event (years) 23.33 21.99 25.16

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 1.74 [1.40, 2.15] 3.6e-7 1564
15 years 0.01 1.23 [1.04, 1.47] 1.7e-2 644
5 years 0.00 1.75 [1.48, 2.08] 6.9e-11 272
1 year 0.00 4.92 [3.99, 6.07] 1.0e-49 141

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: H8_MIDDLEMASTOID – Diseases of middle ear and mastoid
GWS hits: 14

Survival analyses between endpoints

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Plot

before Diseases of middle ear and mastoid
after Diseases of middle ear and mastoid

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Diseases of middle ear and mastoid

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Endpoint not on priority list, no data to show.