Abnormalities of ear ossicles

H8_OSSICABN

Otitis media: Inflammation of the anatomical structures of the middle ear, which is most often caused by an infectious process. Symptoms include erythema and edema of the tympanic membrane, pain, and possibly fever.

Endpoint definition

FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 H74.3
Cause of death: ICD-10 H74.3

2 out of 7 registries used, show all original rules.

55

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Check minimum number of events None

55

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Include endpoints None

55

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Remove individuals based on genotype QC

52

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H8_OSSICABN

Control definitions

Control exclude H8_MIDDLEMASTOID

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 H74
Name in latin Aliae abnormitates acquisitae ossiculorum auditoriorum

Summary Statistics

Key figures

All Female Male
Number of individuals 52 33 19
Unadjusted prevalence (%) 0.01 0.01 0.01
Mean age at first event (years) 48.18 47.07 50.09

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: H8_OSSICABN – Abnormalities of ear ossicles
GWS hits: 1

Survival analyses between endpoints

Plot

before Abnormalities of ear ossicles
after Abnormalities of ear ossicles

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Drugs most likely to be purchased after Abnormalities of ear ossicles

Endpoint not on priority list, no data to show.