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Perforation of tympanic membrane

DOID MESH Endpoint Browser PheWeb

H8_PERFORATION

No definition available.

Endpoint definition

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FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 H72
Hospital discharge: ICD-9 3842
Cause of death: ICD-10 H72
Cause of death: ICD-9 3842

2 out of 7 registries used, show all original rules.

3240

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Check minimum number of events None

3240

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Include endpoints None

3240

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Remove individuals based on genotype QC

3085

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H8_PERFORATION

Control definitions

Control exclude H8_MIDDLEMASTOID

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 H65-H75
Name in latin Perforatio membranae tympanicae

Summary Statistics

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Key figures

All Female Male
Number of individuals 3085 1695 1390
Unadjusted prevalence (%) 0.75 0.74 0.76
Mean age at first event (years) 48.12 45.86 50.88

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.05 2.40 [1.85, 3.13] 5.7e-11 327
15 years 0.01 1.53 [1.18, 1.98] 1.5e-3 162
5 years 0.00 1.95 [1.44, 2.64] 1.6e-5 68
1 year 0.00 2.44 [1.45, 4.12] 8.3e-4 16

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: H8_PERFORATION – Perforation of tympanic membrane
GWS hits: 3

Survival analyses between endpoints

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Plot

before Perforation of tympanic membrane
after Perforation of tympanic membrane

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Drugs most likely to be purchased after Perforation of tympanic membrane

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Endpoint not on priority list, no data to show.