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Disorders of refraction and accommodation

DOID EFO MESH Endpoint Browser PheWeb

H7_REFRAACCOMMODIS

obsolete_refractive error: ['Deviations from the average or standard indices of refraction of the eye through its dioptric or refractive apparatus.']

Endpoint definition

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FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 H52
Cause of death: ICD-10 H52

2 out of 7 registries used, show all original rules.

8999

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Check minimum number of events None

8999

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Include endpoints

9374

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Remove individuals based on genotype QC

8946

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H7_REFRAACCOMMODIS

Control definitions

Control exclude H7_OCUMUSCLE

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 H49-H52
Name in latin Perturbationes refractionis et accommodationis (oculi)

Summary Statistics

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Key figures

All Female Male
Number of individuals 8946 5853 3093
Unadjusted prevalence (%) 2.17 2.54 1.70
Mean age at first event (years) 42.92 41.56 45.47

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.04 1.96 [1.37, 2.81] 2.2e-4 400
15 years 0.01 1.33 [0.89, 1.99] 1.7e-1 208
5 years 0.00 1.95 [1.34, 2.83] 4.8e-4 100
1 year 0.00 3.33 [2.13, 5.19] 1.2e-7 33

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: H7_REFRAACCOMMODIS – Disorders of refraction and accommodation
GWS hits: 1

Survival analyses between endpoints

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Plot

before Disorders of refraction and accommodation
after Disorders of refraction and accommodation

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Disorders of refraction and accommodation

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Endpoint not on priority list, no data to show.