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Astigmatism

DOID EFO MESH Endpoint Browser PheWeb

H7_ASTIGMATISM

obsolete_astigmatism: ['Unequal curvature of the refractive surfaces of the eye. Thus a point source of light cannot be brought to a point focus on the retina but is spread over a more or less diffuse area. This results from the radius of curvature in one plane being longer or shorter than the radius at right angles to it. (Dorland, 27th ed).']

Endpoint definition

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FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 H52.2
Hospital discharge: ICD-9 3672
Hospital discharge: ICD-8 37000
Cause of death: ICD-10 H52.2
Cause of death: ICD-9 3672
Cause of death: ICD-8 37000

2 out of 7 registries used, show all original rules.

1826

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Check minimum number of events None

1826

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Include endpoints None

1826

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Remove individuals based on genotype QC

1697

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H7_ASTIGMATISM

Control definitions

Control exclude H7_OCUMUSCLE

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 H52
Name in latin Astigmatismus

Summary Statistics

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Key figures

All Female Male
Number of individuals 1697 955 742
Unadjusted prevalence (%) 0.41 0.41 0.41
Mean age at first event (years) 42.27 39.21 46.21

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.12 6.21 [4.11, 9.39] 4.1e-18 82
15 years 0.03 4.02 [2.59, 6.22] 4.8e-10 46
5 years 0.00 3.58 [1.94, 6.62] 4.6e-5 21
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: H7_ASTIGMATISM – Astigmatism
GWS hits:

Survival analyses between endpoints

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Plot

before Astigmatism
after Astigmatism

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Astigmatism

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Endpoint not on priority list, no data to show.