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Restless leg syndrome

Endpoint Browser PheWeb

G6_RLS

No definition available.

Endpoint definition

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FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Primary healthcare outpatient: ICD-10: G25.8
Hospital Discharge: ICD-10 G25.8
Cause of death: ICD-10 G25.8

3 out of 7 registries used, show all original rules.

3318

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Check minimum number of events None

3318

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Include endpoints None

3318

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Remove individuals based on genotype QC

3198

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G6_RLS

Control definitions

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF10

Summary Statistics

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Key figures

All Female Male
Number of individuals 3198 2087 1111
Unadjusted prevalence (%) 0.78 0.91 0.61
Mean age at first event (years) 60.73 59.85 62.38

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.07 3.74 [2.49, 5.62] 1.9e-10 196
15 years 0.01 1.46 [0.93, 2.28] 9.8e-2 74
5 years 0.01 3.64 [2.49, 5.33] 2.8e-11 90
1 year 0.00 3.84 [2.27, 6.49] 5.2e-7 20

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: G6_RLS – Restless leg syndrome
GWS hits: 8

Survival analyses between endpoints

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Plot

before Restless leg syndrome
after Restless leg syndrome

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Restless leg syndrome

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Endpoint not on priority list, no data to show.