This is a non-core endpoint: only basic statistics are computed.
Fibrosis and sclerosis of liver
DOID EFO MESH SNOMED Endpoint Browser
FIBROSCLEROLIV
cirrhosis of liver: A disorder characterized by replacement of the liver parenchyma with fibrous tissue and regenerative nodules. It is usually caused by alcoholism, hepatitis B, and hepatitis C. Complications include the development of ascites, esophageal varices, bleeding, and hepatic encephalopathy.
Endpoint definition
↥
FinnGen phenotype data
429209 individuals
Apply sex-specific rule None
429209
Check conditions None
429209
Check pre-conditions, main-only, mode, registry filters
2 out of 7 registries used, show all original rules.
31
Check minimum number of events None
31
Include endpoints None
31
Remove individuals based on genotype QC
30
FIBROSCLEROLIV
Control definitions
Control exclude
CIRRHOSIS_BROAD
Extra metadata
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
K74
Name in latin
Fibrosis et sclerosis hepatis
Show upset plot detailing case counts by codes
Or the full data table
Similar endpoints
↥List of similar endpoints to
Fibrosis and sclerosis of liver
based on the number of shared cases.
Broader endpoints:
- Fibrosis and cirrhosis of liver
- Cirrhosis, broad definition used in the article https://doi.org/10.1101/594523
- Diseases of liver
- Gastrointestinal diseases
- Any operation in hilmo
Narrower endpoints:
None
Summary Statistics
↥Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 30 | 21 | 9 |
| Unadjusted prevalence (%) | 0.01 | 0.01 | 0.00 |
| Mean age at first event (years) | 50.82 | 49.03 | 55.01 |
Mortality
Not a core endpoint, no data to show.
Age distribution of first events
Year distribution of first events
Cumulative Incidence
Not a core endpoint, no data to show.
Correlations
↥
Index endpoint: FIBROSCLEROLIV – Fibrosis and sclerosis of liver
GWS hits:
Survival analyses between endpoints
↥Not a core endpoint, no data to show.
Drugs most likely to be purchased after Fibrosis and sclerosis of liver
↥Endpoint not on priority list, no data to show.