Cardiomyopathy (excluding other)

FG_CARDMYO

cardiomyopathy: A disease of the heart muscle or myocardium proper. Cardiomyopathies may be classified as either primary or secondary, on the basis of etiology, or on the pathophysiology of the lesion: hypertrophic, dilated, or restrictive.

Endpoint definition

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FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters None

0 out of 7 registries used, show all original rules.

0

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Check minimum number of events None

0

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Include endpoints

4580

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Remove individuals based on genotype QC

4458

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FG_CARDMYO

Control definitions

Control exclude FG_OTHHEART

Extra metadata

Level in the ICD hierarchy C
First used in FinnGen datafreeze DF2

Similar endpoints

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Summary Statistics

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Key figures

All Female Male
Number of individuals 4458 1194 3264
Unadjusted prevalence (%) 1.08 0.52 1.80
Mean age at first event (years) 59.77 57.60 60.57

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.10 4.92 [3.45, 7.01] 1.1e-18 1215
15 years 0.02 2.94 [2.31, 3.74] 2.5e-18 492
5 years 0.01 5.45 [4.55, 6.54] 8.1e-75 341
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: FG_CARDMYO – Cardiomyopathy (excluding other)
GWS hits: 15

Survival analyses between endpoints

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Plot

before Cardiomyopathy (excluding other)
after Cardiomyopathy (excluding other)

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Cardiomyopathy (excluding other)

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Endpoint not on priority list, no data to show.