Cardiomyopathy (excluding other)

FG_CARDMYO

cardiomyopathy: A disease of the heart muscle or myocardium proper. Cardiomyopathies may be classified as either primary or secondary, on the basis of etiology, or on the pathophysiology of the lesion: hypertrophic, dilated, or restrictive.

Endpoint definition

FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters None

0 out of 7 registries used, show all original rules.

0

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Check minimum number of events None

0

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Include endpoints

4580

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Remove individuals based on genotype QC

4458

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FG_CARDMYO

Control definitions

Control exclude FG_OTHHEART

Extra metadata

Level in the ICD hierarchy C
First used in FinnGen datafreeze DF2

Similar endpoints

Summary Statistics

Key figures

All Female Male
Number of individuals 4458 1194 3264
Unadjusted prevalence (%) 1.08 0.52 1.80
Mean age at first event (years) 59.77 57.60 60.57

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.10 4.92 [3.45, 7.01] 1.1e-18 1215
15 years 0.02 2.94 [2.31, 3.74] 2.5e-18 492
5 years 0.01 5.45 [4.55, 6.54] 8.1e-75 341
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: FG_CARDMYO – Cardiomyopathy (excluding other)
GWS hits: 15

Survival analyses between endpoints

Plot

before Cardiomyopathy (excluding other)
after Cardiomyopathy (excluding other)

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Cardiomyopathy (excluding other)

Endpoint not on priority list, no data to show.