Precocious puberty

E4_PREPUB

No definition available.

Endpoint definition

FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 E30.1
Hospital discharge: ICD-9 2591
Cause of death: ICD-10 E30.1
Cause of death: ICD-9 2591

2 out of 7 registries used, show all original rules.

151

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Check minimum number of events None

151

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Include endpoints None

151

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Remove individuals based on genotype QC

135

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E4_PREPUB

Control definitions

Control exclude E4_ENDOGLAND

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 E30
Name in latin Pubertas praecox

Summary Statistics

Key figures

All Female Male
Number of individuals 135 113 22
Unadjusted prevalence (%) 0.03 0.05 0.01
Mean age at first event (years) 12.12 10.84 18.70

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: E4_PREPUB – Precocious puberty
GWS hits:

Survival analyses between endpoints

Plot

before Precocious puberty
after Precocious puberty

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Drugs most likely to be purchased after Precocious puberty

Endpoint not on priority list, no data to show.