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Precocious central puberty

Endpoint Browser PheWeb

E4_PRECOXCENTPUB

No definition available.

Endpoint definition

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FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 E22.80, E22.88
Hospital discharge: ICD-9 259
Cause of death: ICD-10 E22.80, E22.88
Cause of death: ICD-9 259

2 out of 7 registries used, show all original rules.

200

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Check minimum number of events None

200

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Include endpoints None

200

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Remove individuals based on genotype QC

185

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E4_PRECOXCENTPUB

Control definitions

Control exclude E4_ENDOGLAND

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF6

Summary Statistics

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Key figures

All Female Male
Number of individuals 185 127 58
Unadjusted prevalence (%) 0.04 0.06 0.03
Mean age at first event (years) 15.74 14.90 17.60

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: E4_PRECOXCENTPUB – Precocious central puberty
GWS hits: 1

Survival analyses between endpoints

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Plot

before Precocious central puberty
after Precocious central puberty

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Precocious central puberty

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Endpoint not on priority list, no data to show.