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Syndrome of inappropriate secretion of antidiuretic hormone

DOID EFO MESH SNOMED Endpoint Browser PheWeb

E4_ANTIDIU

inappropriate ADH syndrome: A syndrome characterized by abnormal secretion of antidiuretic hormone in conjunction with neoplastic growth occurring anywhere in the body.

Endpoint definition

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FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 E22.2
Hospital discharge: ICD-9 2536X
Cause of death: ICD-10 E22.2
Cause of death: ICD-9 2536X

2 out of 7 registries used, show all original rules.

137

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Check minimum number of events None

137

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Include endpoints None

137

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Remove individuals based on genotype QC

133

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E4_ANTIDIU

Control definitions

Control exclude E4_ENDOGLAND

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 E22
Name in latin Syndroma secretionis impropriae hormonis antidiuretici

Summary Statistics

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Key figures

All Female Male
Number of individuals 133 66 67
Unadjusted prevalence (%) 0.03 0.03 0.04
Mean age at first event (years) 66.04 64.38 67.69

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: E4_ANTIDIU – Syndrome of inappropriate secretion of antidiuretic hormone
GWS hits: 1

Survival analyses between endpoints

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Plot

before Syndrome of inappropriate secretion of antidiuretic hormone
after Syndrome of inappropriate secretion of antidiuretic hormone

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Drugs most likely to be purchased after Syndrome of inappropriate secretion of antidiuretic hormone

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Endpoint not on priority list, no data to show.