Drug-induced adrenocortical insufficiency

DRUGADVERS_ADRENOCORTICAL_INSUFFICIENCY

No definition available.

Endpoint definition

FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 E27.3#

1 out of 7 registries used, show all original rules.

455

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Check minimum number of events None

455

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Include endpoints None

455

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Remove individuals based on genotype QC

441

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DRUGADVERS_ADRENOCORTICAL_INSUFFICIENCY

Control definitions

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy C
First used in FinnGen datafreeze DF5

Summary Statistics

Key figures

All Female Male
Number of individuals 441 308 133
Unadjusted prevalence (%) 0.11 0.13 0.07
Mean age at first event (years) 55.92 53.73 60.99

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.13 6.54 [2.07, 20.61] 1.4e-3 31
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: DRUGADVERS_ADRENOCORTICAL_INSUFFICIENCY – Drug-induced adrenocortical insufficiency
GWS hits:

Survival analyses between endpoints

Plot

before Drug-induced adrenocortical insufficiency
after Drug-induced adrenocortical insufficiency

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Drugs most likely to be purchased after Drug-induced adrenocortical insufficiency

Endpoint not on priority list, no data to show.