COPD-related respiratory insufficiency

COPD_INSUFFICIENCY

No definition available.

Endpoint definition

FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions

J10_COPDNAS

19736

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Check pre-conditions, main-only, mode, registry filters None

0 out of 7 registries used, show all original rules.

0

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Check minimum number of events None

0

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Remove individuals based on genotype QC

3677

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COPD_INSUFFICIENCY

Control definitions

Control conditions not J10_COPDNAS

Extra metadata

First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 3677 979 2698
Unadjusted prevalence (%) 0.89 0.43 1.48
Mean age at first event (years) 69.86 66.17 71.20

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.30 17.35 [12.33, 24.42] 3.9e-60 1876
15 years 0.03 3.66 [2.78, 4.83] 3.5e-20 344
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: COPD_INSUFFICIENCY – COPD-related respiratory insufficiency
GWS hits: 2

Survival analyses between endpoints

Plot

before COPD-related respiratory insufficiency
after COPD-related respiratory insufficiency

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Drugs most likely to be purchased after COPD-related respiratory insufficiency

Endpoint not on priority list, no data to show.