This is a non-core endpoint: only basic statistics are computed.
Respiratory insufficiency
DOID EFO MESH SNOMED Endpoint Browser
RESPIRATORYINSUFF
respiratory failure: The significant impairment of gas exchange within the lungs resulting in hypoxia, hypercarbia, or both, to the extent that organ tissue perfusion is severely compromised. Causes include chronic obstructive pulmonary disease, asthma, emphysema, acute respiratory distress syndrome, pneumonia, pulmonary edema, pneumothorax, and congestive heart failure. Treatment requires intubation and mechanical ventilation until the time the lungs recover sufficient function. [NCIT:C26872]
Endpoint definition
↥
FinnGen phenotype data
429209 individuals
Apply sex-specific rule None
429209
Check conditions None
429209
Check pre-conditions, main-only, mode, registry filters
2 out of 7 registries used, show all original rules.
2684
Check minimum number of events None
2684
Include endpoints None
2684
Remove individuals based on genotype QC
2602
RESPIRATORYINSUFF
Control definitions
Control exclude
ASTHMA_EXCL
Extra metadata
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
J96
Name in latin
Insufficientia respiratoria chronica
Show upset plot detailing case counts by codes
Or the full data table
Similar endpoints
↥List of similar endpoints to
Respiratory insufficiency
based on the number of shared cases.
Broader endpoints:
- Other respiratory disorders and diseases
- Other diseases of the respiratory system
- Other diseases of pleura
- Condition for Implicit Sepsis (Organ dysfunction codes)
- Other pulmonary diagnosis
Narrower endpoints:
None
Summary Statistics
↥Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 2602 | 835 | 1767 |
| Unadjusted prevalence (%) | 0.63 | 0.36 | 0.97 |
| Mean age at first event (years) | 69.90 | 66.45 | 71.52 |
Mortality
Not a core endpoint, no data to show.
Age distribution of first events
Year distribution of first events
Cumulative Incidence
Not a core endpoint, no data to show.
Correlations
↥
Index endpoint: RESPIRATORYINSUFF – Respiratory insufficiency
GWS hits:
Survival analyses between endpoints
↥Not a core endpoint, no data to show.
Drugs most likely to be purchased after Respiratory insufficiency
↥Endpoint not on priority list, no data to show.