Cirrhosis of liver, NAS

CHIRHEP_NAS

non-alcoholic fatty liver disease: A term referring to fatty replacement of the hepatic parenchyma which is not related to alcohol use.

Endpoint definition

FinnGen phenotype data

429209 individuals

diagram downward connector

Apply sex-specific rule None

429209

diagram downward connector

Check conditions None

429209

diagram downward connector
diagram bullet

Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 K74.6
Cause of death: ICD-10 K74.6

2 out of 7 registries used, show all original rules.

1306

diagram downward connector

Check minimum number of events None

1306

diagram downward connector

Include endpoints None

1306

diagram downward connector
diagram bullet diagram downward connector

Remove individuals based on genotype QC

1266

diagram downward connector
CHIRHEP_NAS

Control definitions

Control exclude CIRRHOSIS_BROAD

Extra metadata

First used in FinnGen datafreeze DF2
Parent code in ICD-10 K74
Name in latin Cirrhosis hepatis alia sive non specificata

Summary Statistics

Key figures

All Female Male
Number of individuals 1266 504 762
Unadjusted prevalence (%) 0.31 0.22 0.42
Mean age at first event (years) 64.14 62.58 65.17

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: CHIRHEP_NAS – Cirrhosis of liver, NAS
GWS hits: 6

Survival analyses between endpoints

Plot

before Cirrhosis of liver, NAS
after Cirrhosis of liver, NAS

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Cirrhosis of liver, NAS

Endpoint not on priority list, no data to show.