Charcot foot

CHARCOT

No definition available.

Endpoint definition

FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 M14.6*A52.1, M14.6*E10.6, M14.6*E11.6
Cause of death: ICD-10 M14.6*A52.1, M14.6*E10.6, M14.6*E11.6

2 out of 7 registries used, show all original rules.

518

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Check minimum number of events None

518

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Include endpoints None

518

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Remove individuals based on genotype QC

503

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CHARCOT

Control definitions

Control exclude DM_COMORB

Extra metadata

First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 503 197 306
Unadjusted prevalence (%) 0.12 0.09 0.17
Mean age at first event (years) 55.93 53.56 57.46

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.22 11.54 [5.84, 22.79] 1.9e-12 112
15 years 0.05 6.51 [3.27, 12.95] 9.4e-8 59
5 years 0.02 13.06 [7.76, 21.97] 3.7e-22 40
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: CHARCOT – Charcot foot
GWS hits:

Survival analyses between endpoints

Plot

before Charcot foot
after Charcot foot

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Charcot foot

Endpoint not on priority list, no data to show.