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Adult-onset Still disease

DOID EFO MESH SNOMED Endpoint Browser PheWeb

STILL_ADULT

adult-onset Still's disease: adult-onset Still disease (AOSD) is a rare inflammatory multisystem disorder characterized clinically by fever of unknown origin, arthralgia or arthritis, hyperleucocytosis, and typical skin rash.

Endpoint definition

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FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 M06.1
Cause of death: ICD-10 M06.1

2 out of 7 registries used, show all original rules.

132

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Check minimum number of events None

132

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Include endpoints None

132

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Remove individuals based on genotype QC

125

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STILL_ADULT

Control definitions

Control exclude ILD_SYST_AUTO_DISEASES

Extra metadata

First used in FinnGen datafreeze DF5
Parent code in ICD-10 M06
Name in latin Arthritis rheumatoides seronegativa

Summary Statistics

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Key figures

All Female Male
Number of individuals 125 76 49
Unadjusted prevalence (%) 0.03 0.03 0.03
Mean age at first event (years) 46.46 43.84 50.53

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: STILL_ADULT – Adult-onset Still disease
GWS hits:

Survival analyses between endpoints

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Plot

before Adult-onset Still disease
after Adult-onset Still disease

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Adult-onset Still disease

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Endpoint not on priority list, no data to show.