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Spondyloarthritis

Endpoint Browser PheWeb

SPONDYLOARTHRITIS

No definition available.

Endpoint definition

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FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 M45, M45+H22.1, M45+J99.8, M46
Hospital discharge: ICD-9 720
Hospital discharge: ICD-8 7124|7131|72699
Cause of death: ICD-10 M45, M45+H22.1, M45+J99.8, M46
Cause of death: ICD-9 720
Cause of death: ICD-8 7124|7131|72699

2 out of 7 registries used, show all original rules.

7235

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Check minimum number of events None

7235

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Include endpoints None

7235

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Remove individuals based on genotype QC

6991

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SPONDYLOARTHRITIS

Control definitions

Control exclude ILD_SYST_AUTO_DISEASES

Extra metadata

First used in FinnGen datafreeze DF2

Summary Statistics

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Key figures

All Female Male
Number of individuals 6991 3498 3493
Unadjusted prevalence (%) 1.70 1.52 1.92
Mean age at first event (years) 45.45 43.64 47.27

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 1.45 [1.10, 1.92] 9.2e-3 1089
15 years 0.01 1.04 [0.86, 1.27] 6.6e-1 487
5 years 0.00 1.49 [1.23, 1.79] 3.0e-5 214
1 year 0.00 3.12 [2.42, 4.03] 2.8e-18 85

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: SPONDYLOARTHRITIS – Spondyloarthritis
GWS hits: 11

Survival analyses between endpoints

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Plot

before Spondyloarthritis
after Spondyloarthritis

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Spondyloarthritis

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Endpoint not on priority list, no data to show.