≡ Risteys
R10

Documentation Changelog GitHub Contact & Feedback

Ankylosing spondylitis, strict definition

DOID EFO MESH SNOMED Endpoint Browser PheWeb

M13_ANKYLOSPON_STRICT

ankylosing spondylitis: An autoimmune chronic inflammatory disorder characterized by inflammation in the vertebral joints of the spine and sacroiliac joints. It predominantly affects young males. Patients present with stiffness and pain in the spine.

Endpoint definition

↥
FinnGen phenotype data

429209 individuals

diagram downward connector

Apply sex-specific rule None

429209

diagram downward connector
diagram bullet

Check conditions

M13_ANKYLOSPON_ICD10

3059

diagram downward connector
diagram bullet

Check pre-conditions, main-only, mode, registry filters

KELA reimbursements: KELA codes ANY
KELA reimbursements: ICD-10 M45

1 out of 7 registries used, show all original rules.

1438

diagram downward connector

Check minimum number of events None

1438

diagram downward connector

Include endpoints None

1438

diagram downward connector
diagram bullet diagram downward connector

Remove individuals based on genotype QC

1381

diagram downward connector
M13_ANKYLOSPON_STRICT

Control definitions

Control conditions not M13_ANKYLOSPON_ICD10

Extra metadata

Level in the ICD hierarchy C
First used in FinnGen datafreeze DF3

Summary Statistics

↥

Key figures

All Female Male
Number of individuals 1381 643 738
Unadjusted prevalence (%) 0.34 0.28 0.41
Mean age at first event (years) 40.49 39.64 41.22

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.01 0.49 [0.09, 2.60] 4.1e-1 25
15 years 0.00 0.50 [0.11, 2.14] 3.5e-1 11
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

↥

Index endpoint: M13_ANKYLOSPON_STRICT – Ankylosing spondylitis, strict definition
GWS hits: 8

Survival analyses between endpoints

↥

Plot

before Ankylosing spondylitis, strict definition
after Ankylosing spondylitis, strict definition

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Ankylosing spondylitis, strict definition

↥

Endpoint not on priority list, no data to show.