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SLE (Finngen)

DOID MESH Endpoint Browser PheWeb

SLE_FG

No definition available.

Endpoint definition

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FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters None

0 out of 7 registries used, show all original rules.

0

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Check minimum number of events None

0

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Include endpoints

1121

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Remove individuals based on genotype QC

1083

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SLE_FG

Control definitions

Control exclude AUTOIMMUNE

Extra metadata

First used in FinnGen datafreeze DF2

Summary Statistics

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Key figures

All Female Male
Number of individuals 1083 898 185
Unadjusted prevalence (%) 0.26 0.39 0.10
Mean age at first event (years) 45.95 44.87 51.19

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.04 1.88 [0.56, 6.36] 3.1e-1 115
15 years 0.01 1.59 [0.61, 4.14] 3.4e-1 47
5 years 0.00 3.29 [1.52, 7.15] 2.6e-3 26
1 year 0.00 10.35 [4.69, 22.84] 7.1e-9 15

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: SLE_FG – SLE (Finngen)
GWS hits: 7

Survival analyses between endpoints

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Plot

before SLE (Finngen)
after SLE (Finngen)

loading spinner Loading survival analyses plot