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Other/unspecified rheumatoid arthritis

DOID EFO MESH SNOMED Endpoint Browser PheWeb

RHEUMA_NOS

rheumatoid arthritis: A chronic, systemic autoimmune disorder characterized by inflammation in the synovial membranes and articular surfaces. It manifests primarily as a symmetric, erosive polyarthritis that spares the axial skeleton and is typically associated with the presence in the serum of rheumatoid factor.

Endpoint definition

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FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 M06.8, M06.9
Hospital discharge: ICD-9 7148
Hospital discharge: ICD-8 7123[8-9]
Cause of death: ICD-10 M06.8, M06.9
Cause of death: ICD-9 7148
Cause of death: ICD-8 7123[8-9]

2 out of 7 registries used, show all original rules.

4320

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Check minimum number of events None

4320

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Include endpoints None

4320

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Remove individuals based on genotype QC

4216

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RHEUMA_NOS

Control definitions

Control exclude STILL_ADULT

Extra metadata

First used in FinnGen datafreeze DF2

Summary Statistics

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Key figures

All Female Male
Number of individuals 4216 2813 1403
Unadjusted prevalence (%) 1.02 1.22 0.77
Mean age at first event (years) 50.27 48.24 54.33

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.05 2.47 [1.84, 3.31] 1.8e-9 882
15 years 0.01 1.55 [1.23, 1.95] 2.4e-4 333
5 years 0.00 3.11 [2.54, 3.80] 3.6e-28 222
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: RHEUMA_NOS – Other/unspecified rheumatoid arthritis
GWS hits: 5

Survival analyses between endpoints

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Plot

before Other/unspecified rheumatoid arthritis
after Other/unspecified rheumatoid arthritis

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Other/unspecified rheumatoid arthritis

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Endpoint not on priority list, no data to show.