Other diseases of pleura

DOID EFO MESH SNOMED Endpoint Browser PheWeb

J10_PLEURA

respiratory system disease: A non-neoplastic or neoplastic disorder that affects the respiratory system. Representative examples include pneumonia, chronic obstructive pulmonary disease, pulmonary failure, lung adenoma, lung carcinoma, and tracheal carcinoma.

Endpoint definition

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FinnGen phenotype data

429209 individuals

Apply sex-specific rule None

429209

Check conditions None

429209

Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 J90-J94, J95-J99

Cause of death: ICD-10 J90-J94, J95-J99

2 out of 7 registries used, show all original rules.

16149

Check minimum number of events None

16149

Include endpoints

J10_PLEUREFFUSION

J10_PLEURPLAGUE

J10_PNEUMOTHORAX

J10_PLEUROTH

17270

Remove individuals based on genotype QC

16728

J10_PLEURA

Control definitions

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy 2

First used in FinnGen datafreeze DF2

NAME	J10_PLEURA
CONTROL_EXCLUDE
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE	J10_PLEUREFFUSION\|J10_PLEURPLAGUE\|J10_PNEUMOTHORAX\|J10_PLEUROTH
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	J9[0-9]
HD_ICD_9
HD_ICD_8
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	J9[0-9]
COD_ICD_9
COD_ICD_8
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

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Or the full data table

Similar endpoints

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List of similar endpoints to Other diseases of pleura based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	16728	5248	11480
Unadjusted prevalence (%)	4.06	2.28	6.32
Mean age at first event (years)	64.14	61.18	65.49

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.12	5.69 [4.71, 6.88]	5.8e-72	6430
15 years	0.01	2.12 [1.84, 2.44]	7.3e-25	1549
5 years	0.01	6.18 [5.53, 6.91]	<1e-100	1981
1 year	0.01	31.64 [28.47, 35.16]	<1e-100	2533

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: J10_PLEURA – Other diseases of pleura
GWS hits: 3

Survival analyses between endpoints

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Plot

before Other diseases of pleura
after Other diseases of pleura

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Table

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Drugs most likely to be purchased after Other diseases of pleura

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Endpoint not on priority list, no data to show.

≡ Risteys

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