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Cleft lip

DOID EFO MESH Endpoint Browser PheWeb

Q17_CLEFT_LIP

cleft lip: ['Congenital defect in the upper lip where the maxillary prominence fails to merge with the merged medial nasal prominences. It is thought to be caused by faulty migration of the mesoderm in the head region.']

Endpoint definition

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FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 Q36
Hospital discharge: ICD-9 7491[A-G]
Hospital discharge: ICD-8 74910|7491[123]
Cause of death: ICD-10 Q36
Cause of death: ICD-9 7491[A-G]
Cause of death: ICD-8 74910|7491[123]

2 out of 7 registries used, show all original rules.

91

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Check minimum number of events None

91

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Include endpoints None

91

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Remove individuals based on genotype QC

85

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Q17_CLEFT_LIP

Control definitions

Control exclude Q17_CLEFT_LIP_CLEFT_PALATE

Extra metadata

First used in FinnGen datafreeze DF7

Summary Statistics

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Key figures

All Female Male
Number of individuals 85 45 40
Unadjusted prevalence (%) 0.02 0.02 0.02
Mean age at first event (years) 9.87 13.05 6.29

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: Q17_CLEFT_LIP – Cleft lip
GWS hits:

Survival analyses between endpoints

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Not a core endpoint, no data to show.

Drugs most likely to be purchased after Cleft lip

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Endpoint not on priority list, no data to show.