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Renal tubulo-interstitial diseases

DOID MESH Endpoint Browser PheWeb

N14_RENALTUB

No definition available.

Endpoint definition

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FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 N10-N16, N17-N19
Cause of death: ICD-10 N10-N16, N17-N19

2 out of 7 registries used, show all original rules.

38937

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Check minimum number of events None

38937

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Include endpoints

43690

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Remove individuals based on genotype QC

42071

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N14_RENALTUB

Control definitions

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF2

Summary Statistics

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Key figures

All Female Male
Number of individuals 42071 22277 19794
Unadjusted prevalence (%) 10.21 9.68 10.89
Mean age at first event (years) 57.57 49.58 66.56

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.11 5.51 [4.76, 6.37] <1e-100 11063
15 years 0.01 2.13 [1.89, 2.41] 7.1e-35 2618
5 years 0.01 6.31 [5.82, 6.85] <1e-100 3755
1 year 0.01 25.79 [23.56, 28.24] <1e-100 4128

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: N14_RENALTUB – Renal tubulo-interstitial diseases
GWS hits: 2

Survival analyses between endpoints

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Plot

before Renal tubulo-interstitial diseases
after Renal tubulo-interstitial diseases

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Renal tubulo-interstitial diseases

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Endpoint not on priority list, no data to show.