Hydronephrosis

N14_HYDRONEPHR

hydronephrosis: Collection of urine in the renal pelvis that results in dilatation of the renal pelvis and calyces. It is caused by obstruction of urine flow, nephrolithiasis, or vesicoureteral reflux. Signs and symptoms include flank pain, nausea, vomiting, fever, and dysuria.

Endpoint definition

FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 N13.0, N13.1, N13.2, N13.3
Hospital discharge: ICD-9 591
Hospital discharge: ICD-8 591
Cause of death: ICD-10 N13.0, N13.1, N13.2, N13.3
Cause of death: ICD-9 591
Cause of death: ICD-8 591

2 out of 7 registries used, show all original rules.

3683

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Check minimum number of events None

3683

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Include endpoints None

3683

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Remove individuals based on genotype QC

3542

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N14_HYDRONEPHR

Control definitions

Control exclude N14_RENALTUB

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 3542 1677 1865
Unadjusted prevalence (%) 0.86 0.73 1.03
Mean age at first event (years) 58.29 52.59 63.42

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: N14_HYDRONEPHR – Hydronephrosis
GWS hits:

Survival analyses between endpoints

Plot

before Hydronephrosis
after Hydronephrosis

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Hydronephrosis

Endpoint not on priority list, no data to show.