IgA nephropathy (IgA glomerulonephritis)

Endpoint Browser PheWeb

N14_IGA_NEPHROPATHY

No definition available.

Endpoint definition

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FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 N08.2*D89.80

Cause of death: ICD-10 N08.2*D89.80

2 out of 7 registries used, show all original rules.

687

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Check minimum number of events None

687

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Include endpoints None

687

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Remove individuals based on genotype QC

653

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N14_IGA_NEPHROPATHY

Control definitions

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF7

NAME	N14_IGA_NEPHROPATHY
CONTROL_EXCLUDE
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	N082&D8980
HD_ICD_9
HD_ICD_8
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	N082&D8980
COD_ICD_9
COD_ICD_8
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

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Or the full data table

Similar endpoints

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List of similar endpoints to IgA nephropathy (IgA glomerulonephritis) based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	653	234	419
Unadjusted prevalence (%)	0.16	0.10	0.23
Mean age at first event (years)	47.90	43.66	50.27

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.05	2.19 [0.87, 5.49]	9.4e-2	59
15 years	0.01	1.38 [0.57, 3.31]	4.8e-1	23
5 years	0.01	4.32 [2.19, 8.51]	2.3e-5	21
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: N14_IGA_NEPHROPATHY – IgA nephropathy (IgA glomerulonephritis)
GWS hits:

Survival analyses between endpoints

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Plot

before IgA nephropathy (IgA glomerulonephritis)
after IgA nephropathy (IgA glomerulonephritis)

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Table

Loading survival analyses table

Drugs most likely to be purchased after IgA nephropathy (IgA glomerulonephritis)

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Endpoint not on priority list, no data to show.