Migraine, single triptan purchase ok & required. ICD-code if available is included

MIGRAINE_TRIPTAN

migraine disorder: A common, severe type of vascular headache often associated with increased sympathetic activity, resulting in nausea, vomiting, and light sensitivity.

Endpoint definition

FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions

TRIPTAN1

46305

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Check pre-conditions, main-only, mode, registry filters None

0 out of 7 registries used, show all original rules.

0

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Check minimum number of events None

0

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Include endpoints

46305

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Remove individuals based on genotype QC

44615

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MIGRAINE_TRIPTAN

Control definitions

Control conditions not TRIPTAN1

Extra metadata

First used in FinnGen datafreeze DF3

Summary Statistics

Key figures

All Female Male
Number of individuals 44615 37287 7328
Unadjusted prevalence (%) 10.83 16.19 4.03
Mean age at first event (years) 37.14 36.52 40.31

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 1.25 [1.04, 1.50] 1.8e-2 784
15 years 0.01 1.01 [0.84, 1.21] 9.3e-1 317
5 years 0.00 1.30 [1.01, 1.66] 3.8e-2 92
1 year 0.00 2.08 [1.37, 3.16] 6.4e-4 25

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: MIGRAINE_TRIPTAN – Migraine, single triptan purchase ok & required. ICD-code if available is included
GWS hits: 43

Survival analyses between endpoints

Plot

before Migraine, single triptan purchase ok & required. ICD-code if available is included
after Migraine, single triptan purchase ok & required. ICD-code if available is included

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Migraine, single triptan purchase ok & required. ICD-code if available is included

Endpoint not on priority list, no data to show.