Memory loss

MEMLOSS

No definition available.

Endpoint definition

FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 R41.1, R41.2, R41.3
Cause of death: ICD-10 R41.1, R41.2, R41.3

2 out of 7 registries used, show all original rules.

2796

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Check minimum number of events None

2796

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Include endpoints None

2796

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Remove individuals based on genotype QC

2711

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MEMLOSS

Control definitions

Control exclude F5_DEMENTIA, G6_ALZHEIMER, G6_AD_WIDE

Extra metadata

First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 2711 1421 1290
Unadjusted prevalence (%) 0.66 0.62 0.71
Mean age at first event (years) 66.06 64.87 67.37

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.06 2.77 [1.85, 4.16] 8.0e-7 498
15 years 0.01 1.28 [0.88, 1.85] 1.9e-1 196
5 years 0.00 3.55 [2.70, 4.67] 9.9e-20 208
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: MEMLOSS – Memory loss
GWS hits: 1

Survival analyses between endpoints

Plot

before Memory loss
after Memory loss

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Memory loss

Endpoint not on priority list, no data to show.