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Memory loss

DOID MESH Endpoint Browser PheWeb

MEMLOSS

No definition available.

Endpoint definition

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FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 R41.1, R41.2, R41.3
Cause of death: ICD-10 R41.1, R41.2, R41.3

2 out of 7 registries used, show all original rules.

2796

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Check minimum number of events None

2796

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Include endpoints None

2796

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Remove individuals based on genotype QC

2711

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MEMLOSS

Control definitions

Control exclude F5_DEMENTIA, G6_ALZHEIMER, G6_AD_WIDE

Extra metadata

First used in FinnGen datafreeze DF2

Summary Statistics

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Key figures

All Female Male
Number of individuals 2711 1421 1290
Unadjusted prevalence (%) 0.66 0.62 0.71
Mean age at first event (years) 66.06 64.87 67.37

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.06 2.77 [1.85, 4.16] 8.0e-7 498
15 years 0.01 1.28 [0.88, 1.85] 1.9e-1 196
5 years 0.00 3.55 [2.70, 4.67] 9.9e-20 208
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: MEMLOSS – Memory loss
GWS hits: 1

Survival analyses between endpoints

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Plot

before Memory loss
after Memory loss

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Memory loss

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Endpoint not on priority list, no data to show.