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Spinal stenosis

DOID EFO MESH SNOMED Endpoint Browser PheWeb

M13_SPINSTENOSIS

spinal stenosis: Narrowing of the spinal canal.

Endpoint definition

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FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 M48.0
Hospital discharge: ICD-9 7230A|7240
Cause of death: ICD-10 M48.0
Cause of death: ICD-9 7230A|7240

2 out of 7 registries used, show all original rules.

21338

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Check minimum number of events None

21338

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Include endpoints None

21338

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Remove individuals based on genotype QC

20807

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M13_SPINSTENOSIS

Control definitions

Control exclude M13_DORSOPATHY

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 M48
Name in latin Stenosis spinalis

Summary Statistics

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Key figures

All Female Male
Number of individuals 20807 10908 9899
Unadjusted prevalence (%) 5.05 4.74 5.45
Mean age at first event (years) 64.22 63.84 64.65

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.04 1.71 [1.39, 2.11] 6.0e-7 2855
15 years 0.01 1.30 [1.13, 1.50] 3.4e-4 1485
5 years 0.00 1.91 [1.68, 2.17] 1.3e-22 731
1 year 0.00 2.93 [2.45, 3.50] 3.9e-32 207

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: M13_SPINSTENOSIS – Spinal stenosis
GWS hits: 40

Survival analyses between endpoints

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Plot

before Spinal stenosis
after Spinal stenosis

loading spinner Loading survival analyses plot