fibromyalgia: A chronic disorder of unknown etiology characterized by pain, stiffness, and tenderness in the muscles of neck, shoulders, back, hips, arms, and legs. Other signs and symptoms include headaches, fatigue, sleep disturbances, and painful menstruation.

Endpoint definition

FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None


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Check conditions None


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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 M79.1
Hospital discharge: ICD-9 7291
Cause of death: ICD-10 M79.1
Cause of death: ICD-9 7291

2 out of 7 registries used, show all original rules.


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Check minimum number of events None


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Include endpoints None


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Remove individuals based on genotype QC


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Control definitions

Control exclude M13_SOFTTISSUE

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 M79
Name in latin Myalgia

Summary Statistics

Key figures

All Female Male
Number of individuals 7958 5665 2293
Unadjusted prevalence (%) 1.93 2.46 1.26
Mean age at first event (years) 52.27 50.59 56.42


Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.06 2.76 [1.90, 3.99] 7.8e-8 397
15 years 0.01 1.29 [0.85, 1.96] 2.3e-1 152
5 years 0.00 3.31 [2.27, 4.84] 5.6e-10 162
1 year 0.00 5.33 [3.50, 8.12] 6.1e-15 50

Age distribution of first events

Year distribution of first events

Cumulative Incidence


Index endpoint: M13_MYALGIA – Myalgia
GWS hits: 1

Survival analyses between endpoints


before Myalgia
after Myalgia

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Drugs most likely to be purchased after Myalgia

Endpoint not on priority list, no data to show.