Multifocal fibrosclerosis

M13_MULTIFIBRO

multiple sclerosis: A progressive autoimmune disorder affecting the central nervous system resulting in demyelination. Patients develop physical and cognitive impairments that correspond with the affected nerve fibers.

Endpoint definition

FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 M35.5
Cause of death: ICD-10 M35.5

2 out of 7 registries used, show all original rules.

177

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Check minimum number of events None

177

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Include endpoints None

177

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Remove individuals based on genotype QC

172

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M13_MULTIFIBRO

Control definitions

Control exclude M13_SYSTCONNECT

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 M35
Name in latin Fibrosclerosis multifocalis

Summary Statistics

Key figures

All Female Male
Number of individuals 172 119 53
Unadjusted prevalence (%) 0.04 0.05 0.03
Mean age at first event (years) 60.47 58.10 65.79

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: M13_MULTIFIBRO – Multifocal fibrosclerosis
GWS hits:

Survival analyses between endpoints

Plot

before Multifocal fibrosclerosis
after Multifocal fibrosclerosis

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Drugs most likely to be purchased after Multifocal fibrosclerosis

Endpoint not on priority list, no data to show.