Mucocutaneous lymph node syndrome [Kawasaki]

M13_KAWASAKI

mucocutaneous lymph node syndrome: Kawasaki disease (KD) is a febrile, systemic, self-limiting vasculitis affecting children and characterized by inflammation in the medium sized vessels associated with coronary arterial aneurysms (CAA) that may be life threatening when untreated. KD is the most common cause of acquired heart disease in children in developed countries and is a risk factor for ischemic heart disease in adulthood.

Endpoint definition

FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 M30.3
Hospital discharge: ICD-9 4461
Cause of death: ICD-10 M30.3
Cause of death: ICD-9 4461

2 out of 7 registries used, show all original rules.

66

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Check minimum number of events None

66

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Include endpoints None

66

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Remove individuals based on genotype QC

64

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M13_KAWASAKI

Control definitions

Control exclude M13_SYSTCONNECT

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 M30
Name in latin Syndroma mucocutaneum lymphonodorum (Kawasaki)

Summary Statistics

Key figures

All Female Male
Number of individuals 64 35 29
Unadjusted prevalence (%) 0.02 0.02 0.02
Mean age at first event (years) 17.75 16.51 19.24

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: M13_KAWASAKI – Mucocutaneous lymph node syndrome [Kawasaki]
GWS hits:

Survival analyses between endpoints

Not a core endpoint, no data to show.

Drugs most likely to be purchased after Mucocutaneous lymph node syndrome [Kawasaki]

Endpoint not on priority list, no data to show.