Hypersensitivity angiitis

M13_HYPERANG

hypersensitivity vasculitis: Disorder characterized by a vasculitic syndrome associated with exposure to an antigen such as a drug, infectious agent, or other foreign or endogenous substance. Its pathophysiology includes immune complex deposition and a wide range of skin lesions. Hypersensitivity or allergy is present in some but not all cases.

Endpoint definition

FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 M31.0
Hospital discharge: ICD-9 4462A
Hospital discharge: ICD-8 4461
Cause of death: ICD-10 M31.0
Cause of death: ICD-9 4462A
Cause of death: ICD-8 4461

2 out of 7 registries used, show all original rules.

149

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Check minimum number of events None

149

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Include endpoints None

149

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Remove individuals based on genotype QC

146

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M13_HYPERANG

Control definitions

Control exclude M13_SYSTCONNECT

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 M31
Name in latin Angi(i)tis hypersensitivitatis

Summary Statistics

Key figures

All Female Male
Number of individuals 146 70 76
Unadjusted prevalence (%) 0.04 0.03 0.04
Mean age at first event (years) 54.32 54.34 54.29

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: M13_HYPERANG – Hypersensitivity angiitis
GWS hits:

Survival analyses between endpoints

Plot

before Hypersensitivity angiitis
after Hypersensitivity angiitis

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Hypersensitivity angiitis

Endpoint not on priority list, no data to show.